The EXPEDITE Study: Finding new test for ectopic pregnancy

The team aims to develop a new test to rapidly diagnose ectopic pregnancy.

Woman smiling at camera in a lab

Ectopic pregnancies are the leading cause of death and morbidity in mothers in early pregnancy. The symptoms associated with an ectopic pregnancy such as vaginal bleeding and pain are also common in women with a normal pregnancy.

Women experiencing symptoms may have to undergo invasive surgeries to make a definite diagnosis of an ectopic pregnancy. Therefore, Professor Dharani K. Hapangama, University of Liverpool, aims to develop a new test to rapidly diagnose ectopic pregnancy.

Professor Dharani K. Hapangama said: “We believe this proposed work with the combination of novel three dimensional culture models closely simulating an early-pregnancy in the laboratory, novel innovative technology and expertise of basic science and clinical researchers from 3 world renowned centres will produce exciting and clinically useful data to improve the care of millions of women in early pregnancy. We envisage that the study will produce a clinically-applicable non-invasive test which will be suitable for testing in a large multi-centre randomised control trial against the current practise of using an Ultrasound Scan with or without blood test of a single hormone to diagnose presumed ectopic pregnancies. Eventually, we hope that this test will be implemented as routine clinical practise.”